Concerning BPC-157, a natural pentadecapeptide, that acts as a cytoprotectant and is believed to protect the gastro-intestinal tract (GIT).

Inflammopharmacology2025PMID: 40759852

View on PubMed DOI: 10.1007/s10787-025-01882-z

Plain Language Summary

A brief commentary on a comprehensive 2024 BPC 157 review, providing perspective on BPC 157 as a natural pentadecapeptide with cytoprotective effects on the gastrointestinal tract. Discusses its mechanism as a gastric mucosal protective agent and broader systemic effects, offering critical commentary on the evidence base.

Abstract

This article discusses the lengthy review by Pedrag Sikiric and twenty one (21) co-authors in Inflammopharmacology (2024) 32:3119-3161.

Authors

Whitehouse, Michael

Keywords

Organ/ cellular protectionPharmacogeneticsProline-rich peptidesToxicology