Knowledge mapping and research trends of cathelicidin peptide LL-37 from 1995 to 2024: a bibliometric study.

Computer methods in biomechanics and biomedical engineering2025PMID: 40083141

View on PubMed DOI: 10.1080/10255842.2025.2477218

Plain Language Summary

Bibliometric analysis of 2,814 LL-37 publications from 1995-2024 using CiteSpace and VOSviewer. Mapped research trends, identified emerging hotspots, and summarized development patterns in the cathelicidin field, providing a comprehensive overview of the research landscape.

Abstract

BACKGROUND: To conduct a comprehensive bibliometric analysis of LL-37, summarize its development trends and patterns, and identify emerging research hotspots. METHODS: Bibliometric and Knowledge Graph Analysis of Literature Data Related to LL-37 in the WOSCC Database Using Citespace and Vosviewer. RESULTS: A total of 2,814 articles were analyzed, revealing a steady increase in recent publications. The USA and Sweden were the main contributors, with PLOS One publishing the most articles. Research on LL-37 in cancer and mast cells is emerging as a new focus. CONCLUSION: The research status and development trends of LL-37 were quantitatively analyzed, providing new directions for future studies.

Authors

Shi, Hongxin; Shu, Peizhou; Wang, Zhihao; Meng, Chen; Yu, Rao; Xu, YongQing; Li, Chuan

Keywords

CiteSpaceLL-37VOSviewerbibliometric analysiscathelicidin peptide