A review compared two categories of neuroprotective peptides — larger polypeptide complexes like cortexin and cerebrolysin versus shorter synthetic peptides including Semax, kortagen, and pinealon — with a focus on their use in older patients. Both categories show clinical evidence of protecting neurons and supporting brain function, but they work through distinct cellular and molecular pathways. The review provides a useful reference for understanding how different peptide approaches to neuroprotection compare across age groups.
Umnov, R S; Lin'kova, N S; Khavinson, V Kh