[The effect of peptide-type epiphyseal hormones on the functional activity of the human thyroid in vitro. The action of epiphyseal peptides on the accumulation of cyclic nucleotides in the normal human thyroid and on its secretory activity].

Effects of pineal peptides on the accumulation of cyclic nucleotides of the human thyroid and its secretory activity were analysed on the basis of the data obtained after operation from patients with nodular euthyroid goiter) incubated with Epithalamine and Epiphisan, were studied. It was shown, that pineal peptides not only inhibited thyroid secretion function and cAMP accumulation, but also acted as modifiers of TSH stimulatory effects.