BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasing in prevalence as the "go-to" medication for type 2 diabetes, obesity, and off-label weight loss. The changes associated with the use of these medications can result in an undesirable change in facial structure and skin quality, leading to a more aged appearance in users of these medications. This study aimed to identify whether increased public interest in these GLP-1RA-related face changes, a phenomenon termed "Ozempic face," is associated with increased interest in relevant corrective procedures.
METHODS: Google Trends searches for terms related to Ozempic face, and the relevant corrective procedures were statistically analyzed to assess correlative relationships.
RESULTS: A significant positive trend was present for all Ozempic face-related terms from June 2022 to June 2025, indicating an increase in search for these terms during this time period. There was a significant positive relationship between the increased interest in the facial weight loss-related terms and "filler" terms, but no significant relationship with surgical procedure terms.
CONCLUSIONS: With the rapid rise in the number of patients on these medications, it is essential for any clinicians who prescribe them or those who follow up with patients who use them to increase their awareness of this phenomenon for appropriate patient counseling and treatment. This study highlights the growing role of facial aesthetic procedures in the care of GLP-1RA users. Our findings underscore the need for greater clinician education and continued research on the most effective and optimal methods for approaching these side effects.