Diabetes mellitus is an increasingly common long-term metabolic disease. There are many treatment options available to manage type 2 diabetes and reduce the risk of associated long-term microvascular and macrovascular complications. The management of type 2 diabetes initially focuses on lifestyle changes, such as a healthy diet and increased physical activity levels, with pharmacological intervention used as an adjunct where necessary. Tirzepatide, sold under the brand name Mounjaro, is the latest pharmacological therapy to be developed for this condition. This article discusses the place of tirzepatide therapy as part of the management of type 2 diabetes. It explains the mechanism of action of this medicine, its administration and dosing, the potential side effects, and its cautions and contraindications.