[Pathogenesis and diagnosis of dysovarian cardiomyopathy].

Terapevticheskii arkhiv1986PMID: 3824194

Plain Language Summary

Epithalamin was used as a diagnostic tool for dysovarian cardiomyopathy, where its administration normalized gonadotropic hormone levels and improved clinical symptoms in patients. The study revealed a connection between sex hormone metabolism disturbances, pineal gland function, and the development of this cardiac condition.

Abstract

Altogether 78 patients with dysovarian cardiomyopathy were examined, of them in 19 patients the FSH, LH, prolactin, estradiol and testosterone levels were studied. Function of the epiphysis was evaluated by melatonin excretion with urine in 46 patients. Correlation of the metabolism of sex hormones and function of the epiphysis was shown. It was assumed that the effect of disturbance of the metabolism of sex hormones on the myocardium was expressed in change of electrolyte metabolism. A new method was proposed for the diagnosis of dysovarian cardiomyopathy with the help of a pharmacological drug epithalamin whose administration returned the level of the gonadotropic hormones to normal and was accompanied by positive time course of a clinical picture of disease.

Authors

Karpov, R S; Slepushkin, V D; Mordovin, V F; Zykova, V A; Khavinson, V Kh