Influence of pineal peptides on the dynamics of the circadian and minute motor biorhythms in rats.

Neuroscience and behavioral physiology1991PMID: 1876268

Animal StudyEpitalon

Plain Language Summary

Epithalamin exerted a modulating influence on the circadian fluctuations of motor activity in rats and decreased the amplitude of apomorphine-induced stereotypy. These findings suggest that pineal peptides help maintain homeostasis by stabilizing rhythmic biological processes across various time scales.

Abstract

A peptide preparation of the pineal, epithalamin, when administered chronically, exerts a modulating influence on the diurnal fluctuations of the motoric activity of rats. It also decreases the amplitude of apomorphine stereotypy and induces a restructuring of a modulatory character in its rhythmic structure. It is hypothesized that the pineal peptides participate in the maintenance of homeostasis by means of the stabilization of rhythmic processes of various periods.

Authors

Arushanyan, E B; Baturin, V A; Ovanesov, K B