Peptide correction of age-related hormonal dysfunction of the pancreas in monkeys.

Bulletin of experimental biology and medicine2004PMID: 15514731

Animal StudyEpitalon

Plain Language Summary

Epitalon corrected age-related glucose intolerance and restored normal insulin dynamics in old rhesus monkeys. After treatment, older monkeys showed improved ability to process glucose loads, with insulin responses more closely resembling those of young animals.

Abstract

We studied the effect of Epithalon on the function of pancreatic islets and regulation of blood glucose level in female rhesus monkeys of various ages. Epithalon corrected the age-related decrease in glucose tolerance and restored the dynamics of insulin level in response to glucose load.

Authors

Goncharova, N D; Vengerin, A A; Khavinson, V Kh; Lapin, B A