Effects of peptides on proliferative activity of retinal and pigmented epithelial cells.

Bulletin of experimental biology and medicine2003PMID: 12937684

Plain Language Summary

Both the retinal peptide preparation Retinalamin and Epitalon stimulated cell growth in retinal and pigmented epithelial cell cultures in a tissue-specific manner. At certain concentrations, these peptides enhanced the proliferative activity of eye cells, supporting their potential use in treating retinal degenerative conditions.

Abstract

We studied the effects of Retinalamin (polypeptide preparation isolated from the retina) and a synthetic peptide Epithalon (Ala-Glu-Asp-Gly) on proliferative activity of retinal and pigmented epithelial cells. Experiments showed that Retinalamin and Epithalon (in certain concentrations) tissue-specifically stimulated proliferation of retinal and pigmented epithelial cell in culture.

Authors

Khavinson, V Kh; Zemchikhina, V N; Trofimova, S V; Malinin, V V