Effect of epithalon on age-specific changes in the retina in rats with hereditary pigmentary dystrophy.

Bulletin of experimental biology and medicine2002PMID: 12170316

Animal StudyEpitalon

Plain Language Summary

Epitalon administered from birth protected against hereditary retinal degeneration in Campbell rats, preserving the retina's structural integrity, increasing its electrical activity, and improving visual function. These findings suggest early treatment with this pineal peptide can significantly slow the progression of inherited retinal diseases.

Abstract

The effect of peptide bioregulator Epithalon on the course of hereditary pigmentary retinal degeneration was studied in Campbell rats. Administration of epithalon starting from birth protected morphological structure, increased its bioelectrical activity, and improved its function.

Authors

Khavinson, V Kh; Razumovskii, M I; Trofimova, S V; Grigor'yan, R A; Chaban, T V; Oleinik, T L; Razumovskaya, A M