Acute hypobaric hypoxia of pregnant rats led to a significant delay in body weight gain, growth and time of eye opening in newborn rat pups which was paralleled by behavioral changes. Preventive intranasal instillations of peptide mixture (semax and beta-casomorphine-7) to pregnant females prevented the effect of hypoxia on the progeny.
Authors
Maslova, M V; Zemlyanskii, K S; Shkol'nikova, M V; Maklakova, A S; Krushinskaya, Y V; Sokolova, N A; Ashmarin, I P