Regulating effect of epithalone on gastric endocrine cells in pinealectomized rats.

Bulletin of experimental biology and medicine2000PMID: 11276313

Animal StudyEpitalon

Plain Language Summary

Epitalon regulated the function of endocrine cells in the stomachs of pinealectomized rats, as demonstrated by immunohistochemical and morphometric analysis. The findings reveal a functional relationship between the pineal gland and stomach that is mediated by pineal peptides.

Abstract

Endocrine cells in the stomach of pinealectomized rats after injection of epithalone (pineal gland peptide) were studied by immunohistochemical tests, morphometry, and image analysis microscopic images. A functional relationship was found between the pineal gland and stomach, which is regulated by peptides produced by the pineal gland.

Authors

Khavinson, V K; Popuchiev, V V; Kvetnoii, I M; Yuzhakov, V V; Kotlova, L N