A synthetic analog of the immunomodulatory peptide tuftsin, studied for anxiolytic and nootropic effects.
BACKGROUND: Ecological stoichiometry serves as a foundational framework for understanding plant nutrient acquisition, allocation, and conservation strategies in extreme environments. The Wudalianchi volcanic lava platform represents a naturally oligo…
Therapeutic peptides are emerging as promising adjuncts in the management of orthopaedic injuries, grounded in their ability to modulate molecular signaling networks central to cellular medicine. By acting on key pathways such as PI3K/Akt, mTOR, MAPK…
OBJECTIVES: Androgen and TGF-β1/Smad signaling pathways play important roles in epithelial-mesenchymal transition (EMT), fibrosis, and the development of benign prostatic hyperplasia (BPH). Cinnamophilin is extracted from. The anti-proliferative and…
BACKGROUND: Primary Sjögren's disease (SjD) is a chronic autoimmune disease that predominantly affects exocrine glands but can also show numerous systemic organ manifestations. OBJECTIVE: Presentation of the current understanding of the pathogenesis…
BACKGROUND: There are no optimized patient blood management (PBM) protocols for brain tumor resection (BTR). The aim of this study was to compare the prevalence of packed red cells (PRCs) units reserved with the prevalence of transfusion during BTR a…
Nitrogen (N) and phosphorus (P) are widely recognized as primary drivers of eutrophication, yet translating ambient nutrient concentrations into predictive assessments of benthic algal limitation remains challenging. In particular, statewide analyses…
We studied the reparative and antioxidant effects of thymogen (10 and 100 μg/kg) and its modifications in equimolar doses (12 and 120 μg/kg) obtained by attaching the amino acid D-alanine (D-Ala) to the N- or C-terminus of the peptide molecule. A sin…
Anaerobic digestion (AD) is a useful process that could be utilized for food waste (FW) management. Previous studies have shown that carbon materials (CMs) could be an important additive for increasing biomethane yield. However, why CMs improve AD is…
PURPOSE: To investigate the combined effects of oral nutritional supplement (ONS) and intestinal microecology on postoperative nutrition status, inflammatory response and intestinal flora regulation colorectal cancer (CRC) patients. METHODS: This pro…
This clinical study combined alanyl-glutamine and omega-3 polyunsaturated fatty acids (ω-3 PUFAs) to investigate the effects of parenteral nutrition on postoperative inflammation and nutritional status in patients with gastroduodenal perforation to p…
This study explored relationship between concentrations of perchlorate, nitrate, and thiocyanate and serum liver function markers using data from 3366 adults in the 2013-2018 National Health and Nutrition Examination Survey (NHANES) of the United Sta…
Five polypeptides with a potential umami taste were isolated and purified from Yanjin black bone chicken. However, the flavor characteristics and umami mechanism have not been clarified. The umami properties of these five peptides were investigated i…
In patients with interstitial lung disease (ILD), the risk of pulmonary embolism (PE) is increased; however, distinguishing between PE and ILD exacerbation can be difficult. Therefore, this study investigated the usefulness of the Wells criteria and…
Three aquatic macrophytes were used to treat wastewater using a pilot-constructed wetland (CW) system to determine the most efficient plants for removing contaminants from wastewater. The three macrophytes are water hyacinth (), water lettuce (), and…
BACKGROUND: We observed an increase in the frequency of false-positive (FP) human immunodeficiency virus (HIV) test results that correlated with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) prevalence. We measured FP rates of laborato…
Frass is the main component of worm by-product which exhibit anti-microbial and anti-pathogenic properties. In the present study, we assessed the possibility of mealworm frass in sheep feeding regime and evaluated its effect on health and growth perf…
AIMS: Atrial fibrillation (AF) is associated with tachycardia-induced cellular electrophysiology alterations which promote AF chronification and treatment resistance. Development of novel antiarrhythmic therapies is hampered by the absence of scalabl…
MicroRNAs have been projected as promising tools for diagnostic and prognostic purposes in cancer. More recently, they have been highlighted as RNA therapeutic targets for cancer therapy. Though miRs perform a generic function of post-transcriptional…
Activity of a peptide tuftsin analogue Selank was studied in outbred rats using the naloxone-precipitated morphine withdrawal model. Single intraperitoneal injection of Selank in an anxiolytic dose of 0.3 mg/kg reduced the total index of morphine wit…
Background: Thrombocytopenia (TP), a common occurrence among patients admitted to the intensive care unit (ICU), is significantly associated with prolonged ventilator use, prolonged ICU stay, and increased mortality. The duration of TP serves as an i…